反应详情

Combine (5,6-dichloro-pyridin-3-yl)-methanol (3.05 g, 17.11 mmol) and manganese dioxide (37.2 g, 427.9 mmol) in CH2Cl2 (25 mL). Stir the reaction mixture at rt overnight. Filter the reaction mixture through Celite® washing with CH2Cl2 (2× 10 mL). Concentrate the filtrate and dry under vacuum to provide the title compound (1.44 g, 48%).

1. filtrationFilter the reaction mixture through Celite®
2. washwashing with CH2Cl2 (2× 10 mL)
3. concentrationConcentrate the filtrate
4. customdry under vacuum