(5,6-Dichloropyridin-3-yl)methanol → 5,6-Dichloropyridine-3-carbaldehyde

Participants

Reaction Steps

Combine (5,6-dichloro-pyridin-3-yl)-methanol (3.05 g, 17.11 mmol) and manganese dioxide (37.2 g, 427.9 mmol) in CH2Cl2 (25 mL). Stir the reaction mixture at rt overnight. Filter the reaction mixture through Celite® washing with CH2Cl2 (2× 10 mL). Concentrate the filtrate and dry under vacuum to provide the title compound (1.44 g, 48%).

Provenance & Evidence