反应详情

To a solution of 1,4-bis[5-[3,5-bis(methoxymethyl)phenyl]-2-pyridyl]hexahydro-1,4-diazepine (51.9 mg, 0.0892 mmol) in ethanol (5.0 mL) was added 1.0 M hydrochloric acid (0.21 mL, 0.21 mmol), and the reaction mixture was concentrated under reduced pressure. Ethanol (5.0 mL) was added to the residue and the resulting mixture was concentrated under reduced pressure to yield the title compound as a colorless amorphous powder (47.8 mg, yield: 92%).

1. concentrationthe reaction mixture was concentrated under reduced pressure
2. additionEthanol (5.0 mL) was added to the residue
3. concentrationthe resulting mixture was concentrated under reduced pressure