Water → 3-methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one

Participants

Reaction Steps

0.5 g (4.44 mmol) of 2-hydrazinopyridine and 0.58 g (4.44 mmol) of acetoacetic ester are stirred in 15 ml of glacial acetic acid for 2 hours at 90° C. The mixture is then diluted with water and the precipitated crystals are filtered off with suction, washed again with water and dried under reduced pressure.

Provenance & Evidence