HuagongsheHuagongshe Chemistry Print Report · For research reference only
Vanillin → HCID 136385054, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Vanillin | HCID 1183 | — |
| Reactant | Piperidine | HCID 8082 | — |
| Reactant | 3-methyl-1-(pyridin-2-yl)-4,5-dihydro-1H-pyrazol-5-one | HCID 667652 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 136385054 | HCID 136385054 | — |
Reaction Steps
1.4 g (7.99 mmol) of 5-methyl-2-(2-pyridinyl)-2,4-dihydro-3H-pyrazol-3-one and 1.84 g (11.98 mmol) of 4-hydroxy-3-methoxybenzaldehyde are stirred under reflux with the addition of 3 ml of piperidine in absolute ethanol for 2 hours. The mixture is then diluted with water and slowly rendered neutral with 2N hydrochloric acid. After cooling in the ice bath, the orange precipitate which settles out is filtered off, washed with water and dried under reduced pressure.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07534273B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-cac1709724a94b3abd666a1af67534bc |
| Source note | uspto-grants-2009_05 |