反应详情

Methanol (150 ml) and an aqueous solution of 1N-potassium hydroxide (100 ml) were added to 14.2 g (65.7 mmol) of 1-(4-n-propylphenyl)-2-trimethylsilylacetylene synthesized in the step (i), and the mixture was subjected to hydrolysis with vigorously stirring overnight. After completion of the reaction, methanol was removed and the resultant residue was extracted with hexane. After removing hexane from the hexane phase, the resultant residue was washed with water to give 9.4 g (65.3 mmol) of 4-n-propylphenylacetylene.

1. customsynthesized in the step (i)
2. customthe mixture was subjected to hydrolysis
3. customwas removed
4. extractionthe resultant residue was extracted with hexane
5. customAfter removing hexane from the hexane phase
6. washthe resultant residue was washed with water