Potassium Hydroxide → 1-Ethynyl-4-propylbenzene

Participants

Reaction Steps

Methanol (150 ml) and an aqueous solution of 1N-potassium hydroxide (100 ml) were added to 14.2 g (65.7 mmol) of 1-(4-n-propylphenyl)-2-trimethylsilylacetylene synthesized in the step (i), and the mixture was subjected to hydrolysis with vigorously stirring overnight. After completion of the reaction, methanol was removed and the resultant residue was extracted with hexane. After removing hexane from the hexane phase, the resultant residue was washed with water to give 9.4 g (65.3 mmol) of 4-n-propylphenylacetylene.

Provenance & Evidence