Ethanol → Ethyl 4'-hydroxy-4-biphenylcarboxylate

HRID 493044Notes

Reaction equation

HRID 493044 reaction equation
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([OH:14])=[O:13])=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[CH2:17](O)[CH3:18].C(C1C=CC(C(O)=O)=CC=1)CC>CO>[OH:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:16]=[CH:15][C:11]([C:12]([O:14][CH2:17][CH3:18])=[O:13])=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

Participants

5

Reactant 3

HCID 702EthanolHCID 1376014-Propylbenzoic acidHCID 3015564'-Hydroxy-4-biphenylcarboxylic acid

Product 1

HCID 4049156Ethyl 4'-hydroxy-4-biphenylcarboxylate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

The reaction was conducted in the same manner as in the step (i) of the Example 33, except for using 4-(4-hydroxyphenyl)benzoic acid and ethanol in lieu of 4-n-propylbenzoic acid and methanol, respectively, and the resultant was recrystallized from toluene to give ethyl 4-(4-hydroxyphenyl)benzoate.

Workup

  1. customrespectively, and the resultant was recrystallized from toluene

Sources & evidence

ORD record
ord-9202b041f1b14830b03a07aa49b22dea
Source dataset
uspto-grants-2009_05
Patent number
US07534547B2

Reaction notes

Loading…