Hydrochloric Acid → HCID 131723546, compound

HRID 493258Notes

Reaction equation

HRID 493258 reaction equation
[Cl:1][C:2]1[C:11]([O:12][CH2:13][CH2:14][O:15][C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[N:10][C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.Cl>>[ClH:1].[O:15]([CH2:14][CH2:13][O:12][C:11]1[C:2]([N:3]2[CH2:4][CH2:9][NH:10][CH2:11][CH2:2]2)=[N:3][C:4]2[C:9](=[CH:8][CH:7]=[CH:6][CH:5]=2)[N:10]=1)[C:16]1[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 22036340HCID 22036340, compound

Product 1

HCID 131723546HCID 131723546, compound

Procedure

The title compound was prepared according to the procedure described in Example 1, Step 2, starting from 2-chloro-3-(2-phenoxyethoxy)quinoxaline (0.65 g, 2 15 mmol) yield 0.44 g (58%) as the free base A portion of the free base was converted to its hydrochloride salt mp 123-126° C.; HRMS m/z calcd for C20H22N4O2 (M)+ 350.1743, found 350.1748 Anal. (C20H22N4O2.1.75 HCl .0.5 H2O) C, H, N.

Sources & evidence

ORD record
ord-92c5a931a1834b46bce600cb056326f2
Source dataset
uspto-grants-2009_05
Patent number
US07534794B2

Reaction notes

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