2-Methylpiperazine → HCID 22036543, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described In Example 4, Step 2, starting from 2-chloro-3-(2-phenoxyethoxy)pyrazine (150 mg, 0.54 mmol; from Example 1, Step 1) and 2-methylpiperazine (250 mg, 2.5 mmol) with the exception that a final extraction step between EtOAc and 5% aqueous NaOH was carried out This gave 138 mg (73%) of the title product. Anal. (C17H22N4O2) C, H, N.

Provenance & Evidence