HRID49338

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

HCID10717451

(3-Carboxypropyl)(triphenyl)phosphanium bromide

C22H22BrO2P

结构：CCC(=O)c1ccc(CCc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1

HCID20636286

未命名化合物

HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

PRODUCTS

生成物

$结构：CC/C(=C\CCC(=O)O)c1ccc(CCc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)s1$

HCID69825231

未命名化合物

PROCEDURE

实验过程

In a manner similar to that of Example 6(i), by reaction of 5.08 g (9.5 mmol) of 1-{5-[2-(3,4-bis(tert-butyldimethylsilanyloxymethyl)phenyl)ethyl]-2-thienyl}-1-propanone with 6.1 g (14 mmol) of (3-carboxypropyl)triphenylphosphonium bromide and 3.1 g (28 mmol) of potassium tert-butoxide, the desired product is obtained in the form of a yellow oil (m=2.7 g; Y=48%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4b74ece7c24142998258a00b71333e48
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06706725B1
来源说明: uspto-grants-2004_03

反应 SMILES

[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH2:25][CH2:26][C:27]2[S:31][C:30]([C:32](=O)[CH2:33][CH3:34])=[CH:29][CH:28]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][O:17][Si:18]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:20])[CH3:19])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[Br-].[C:37]([CH2:40]CC[P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([OH:39])=[O:38].[CH3:62][C:63](C)([O-])C.[K+]>>[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH2:25][CH2:26][C:27]2[S:31][C:30](/[C:32](/[CH2:62][CH3:63])=[CH:33]/[CH2:34][CH2:40][C:37]([OH:39])=[O:38])=[CH:29][CH:28]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][O:17][Si:18]([C:21]([CH3:22])([CH3:23])[CH3:24])([CH3:20])[CH3:19])([C:4]([CH3:5])([CH3:7])[CH3:6])([CH3:2])[CH3:3]