HRID49354

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)CCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

HCID10717451

(3-Carboxypropyl)(triphenyl)phosphanium bromide

C22H22BrO2P

结构：CCC(=O)c1cc(CCc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)cs1

HCID20636284

未命名化合物

HCID23665647

2-Methyl-2-propanol, potassium salt

C4H9KO

PRODUCTS

生成物

$结构：CC/C(=C\CCC(=O)O)c1cc(CCc2ccc(CO[Si](C)(C)C(C)(C)C)c(CO[Si](C)(C)C(C)(C)C)c2)cs1$

HCID69825156

未命名化合物

PROCEDURE

实验过程

In a manner similar to that of Example 6(i), by reaction of 3 g (5.6 mmol) of 1-{4-[2-(3,4-bis(tert-butyldimethylsilanyloxymethyl)phenyl)ethyl]-2-thienyl}-1-propanone with 3.6 g (8.4 mmol) of (3-carboxy-propyl)triphenylphosphonium bromide and 1.9 g (17 mmol) of potassium tert-butoxide, the desired product is obtained in the form of a yellow oil (m=1.7 g, Y=50%).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-2c741ead76fc4fa6ad942e1ad7df089c
来源数据集: uspto-grants-2004_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06706725B1
来源说明: uspto-grants-2004_03

反应 SMILES

[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH2:25][CH2:26][C:27]2[CH:28]=[C:29]([C:32](=O)[CH2:33][CH3:34])[S:30][CH:31]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][O:17][Si:18]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:20])[CH3:19])([C:4]([CH3:7])([CH3:6])[CH3:5])([CH3:3])[CH3:2].[Br-].[C:37]([CH2:40][CH2:41][CH2:42][P+](C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)([OH:39])=[O:38].CC(C)([O-])C.[K+]>>[Si:1]([O:8][CH2:9][C:10]1[CH:11]=[C:12]([CH2:25][CH2:26][C:27]2[CH:28]=[C:29](/[C:32](/[CH2:33][CH3:34])=[CH:42]/[CH2:41][CH2:40][C:37]([OH:39])=[O:38])[S:30][CH:31]=2)[CH:13]=[CH:14][C:15]=1[CH2:16][O:17][Si:18]([C:21]([CH3:24])([CH3:23])[CH3:22])([CH3:20])[CH3:19])([C:4]([CH3:7])([CH3:5])[CH3:6])([CH3:2])[CH3:3]