Methyl 2-(bromomethyl)-5-chlorobenzoate → 5-Chloro-2-(isobutoxymethyl)benzoic acid

HRID 493553Notes

Reaction equation

HRID 493553 reaction equation
Br[CH2:2][C:3]1[CH:12]=[CH:11][C:10]([Cl:13])=[CH:9][C:4]=1[C:5]([O:7]C)=[O:6]>CC(C)CO>[Cl:13][C:10]1[CH:11]=[CH:12][C:3]([CH2:2][O:6][CH2:5][CH:4]([CH3:9])[CH3:3])=[C:4]([CH:9]=1)[C:5]([OH:7])=[O:6]

Participants

3

Reactant 1

HCID 51358462Methyl 2-(bromomethyl)-5-chlorobenzoate

Product 1

HCID 688636975-Chloro-2-(isobutoxymethyl)benzoic acid

Reagents, catalysts & solvents 1

HCID 6560IsobutanolSolvent

Procedure

The title compound was prepared according to the procedure described in step 1 of Example 16 from methyl 2-(bromomethyl)-5-chlorobenzoate and 2-methylpropan-1-ol:

Sources & evidence

ORD record
ord-2c5dc60f0fa7497eb2d1038641e37aa6
Source dataset
uspto-grants-2009_05
Patent number
US07534914B2

Reaction notes

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