反应详情

A mixture of the 1,2-phenylene-diamine derivative (1 g) and the 2-oxo-carboxylic acid derivative (1 eq) in dry EtOH (35 mL) was stirred at reflux for 2 h under nitrogen. After cooling, the EtOH was evaporated to give a crude brown solid. Recrystallisation from EtOH gave the desired quinoxalin-2-one derivative.

1. temperatureat reflux for 2 h under nitrogen
2. temperatureAfter cooling
3. customthe EtOH was evaporated
4. customto give a crude brown solid
5. customRecrystallisation from EtOH