HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Ethylpiperazine → 4-[(4-Ethyl-1-piperazinyl)methyl]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Ethylpiperazine | HCID 79196 | — |
| Reactant | HCID 21994195 | HCID 21994195 | — |
| Product | 4-[(4-Ethyl-1-piperazinyl)methyl]-1-piperidinecarboxylic acid, 1,1-dimethylethyl ester | HCID 53551746 | 78% |
Reaction Steps
In operating analogously to preparation LXXIII, starting with N-ethylpiperazine and the t-butyl ester of 4-formyl-1-piperidinecarboxylic acid, the product sought after is obtained as a colourless oil (yield=78%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538111B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-828ff378b40d4d1ebf37dbff17c36249 |
| Source note | uspto-grants-2009_05 |