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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494180Generated: October 30, 2026

2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- → Ethyl 6-(4-fluorophenyl)-2-methylpyridine-3-carboxylate

https://huagongshe.com/reaction/494180

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Butenoic acid, 3-amino-, ethyl ester, (2Z)-HCID 643756—
ReactantHCID 18755062HCID 18755062—
ProductEthyl 6-(4-fluorophenyl)-2-methylpyridine-3-carboxylateHCID 11345961—

Reaction Steps

The title compound was prepared from dimethylamino-(4-fluorophenyl)propan-1-one and ethyl 3-aminocrotonate using the general procedure outlined in D18. MS (ES): MH+ 260.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538121B2
Source datasetuspto-grants-2009_05
ORD IDord-9b3ff070b454430ca3ff0a600fe0c8a5
Source noteuspto-grants-2009_05