HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Aminoquinoline → 6-(3-Fluorophenyl)-N-quinolin-7-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Aminoquinoline | HCID 11377 | — |
| Reactant | 6-(3-Fluorophenyl)nicotinic acid | HCID 24729972 | — |
| Product | 6-(3-Fluorophenyl)-N-quinolin-7-yl-nicotinamide | HCID 44578895 | — |
Reaction Steps
Using the procedure outlined in Example 104, the title compound was prepared from 7-aminoquinoline (D55) (28 mg, 0.19 mmol) and 6-(3-fluorophenyl)-nicotinic acid (D73) (50 mg, 0.23 mmol) as a yellow solid. MS(ES): MH+ 344, M-H+ 342
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538121B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-ada6d424bf8c49c681b13dcd191d6a34 |
| Source note | uspto-grants-2009_05 |