HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Aminoquinoline → 6-(4-Fluorophenyl)-2-methyl-N-quinolin-7-yl-nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Aminoquinoline | HCID 11377 | — |
| Reactant | 6-(4-Fluorophenyl)-2-methylpyridine-3-carboxylic acid | HCID 24277790 | — |
| Product | 6-(4-Fluorophenyl)-2-methyl-N-quinolin-7-yl-nicotinamide | HCID 44578988 | — |
Reaction Steps
Using the procedure outlined in Example 45, the title compound was prepared from 7-aminoquinoline (D55) (26 mg, 0.8 mmol) and 6-(4-fluorophenyl)-2-methylnicotinic acid (D24) (50 mg, 0.22 mmol) as a white solid. MS(ES): MH+ 358, M-H+ 356.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538121B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-9bcdbd1012104c0bb3859ac734515f0a |
| Source note | uspto-grants-2009_05 |