Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494285Generated: October 30, 2026

(1,1'-Biphenyl)-4-carboxylic acid → HCID 44415687, compound

https://huagongshe.com/reaction/494285

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(1,1'-Biphenyl)-4-carboxylic acidHCID 66724—
Reactant7-Aminoquinolin-2(1H)-oneHCID 18941542—
ProductHCID 44415687HCID 44415687—

Reaction Steps

Using the procedure outlined in Example 56, the title compound was prepared from 7-amino-1H-quinolin-2-one (D89) (30 mg, 0.19 mmol) and 4-biphenylcarboxylic acid (44 mg, 0.22 mmol) as an off-white solid. 1H NMR (400 MHz, DMSO) δ (ppm): 11.80 (br, 1H), 10.58 (br, 1H), 8.09 (d, 2H), 8.04 (d, 1H), 7.85 (m, 3H), 7.77 (d, 2H), 7.62 (d, 1H), 7.52 (m, 3H), 7.44 (t, 1H), 6.39 (d, 1H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538121B2
Source datasetuspto-grants-2009_05
ORD IDord-d37fdcb32f19454096fed0e58cf668e7
Source noteuspto-grants-2009_05