HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57683030, compound → HCID 57683016, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57683030 | HCID 57683030 | — |
| Reactant | HCID 57683060 | HCID 57683060 | — |
| Product | HCID 57683016 | HCID 57683016 | 43% |
Reaction Steps
According to the procedure described for the synthesis of 4-(5-methyl-3-(4-fluorophenyl)-isoxazole-4-carbonyl)-1-methyl-pyrrole-2-carboxylic acid (cyclopropylmethyl)-amide (Example 229, step 3), the title compound was synthesized from 4-[5-methyl-3-(3-fluorophenyl)-isoxazole-4-carbonyl)-1H-pyrrole-2-carboxylic acid prop-2-ynylamide (example 179) in 43% yield as white solid. (m/e): 366.1 (M+1; 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538132B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-a78de0f9d2114c07a8574f0c5f01e036 |
| Source note | uspto-grants-2009_05 |