HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 57480100, compound → HCID 57683003, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 57480100 | HCID 57480100 | — |
| Reactant | HCID 57683030 | HCID 57683030 | — |
| Product | HCID 57683003 | HCID 57683003 | 34.2% |
Reaction Steps
According to the procedure described for the synthesis of 4-(5-methyl-3-(4-fluorophenyl)-isoxazole-4-carbonyl)-1-methyl-pyrrole-2-carboxylic acid (cyclopropylmethyl)-amide (Example 229, step 3), the title compound was synthesized from 4-[5-methyl-3-(3-fluorophenyl)-isoxazole-4-carbonyl)-1H-pyrrole-2-carboxylic acid cyclobutylamide (example 174) in 34.2% yield as white solid. (m/e): 382.1 (M+1; 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538132B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-37d5a65fad5a4ed4bda2a1dc282d5e23 |
| Source note | uspto-grants-2009_05 |