HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropanemethanamine → HCID 57683039, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropanemethanamine | HCID 75646 | — |
| Reactant | HCID 57682986 | HCID 57682986 | — |
| Reactant | HCID 57683183 | HCID 57683183 | — |
| Product | HCID 57683039 | HCID 57683039 | — |
Reaction Steps
According to the procedure described for the synthesis of 4-(5-methyl-3-(4-fluorophenyl)-isoxazole-4-carbonyl)-1H-pyrrole-2-carboxylic acid (cyclopropylmethyl)-amide (example 229, step 2), the title compound has been synthesized from 4-[3-(3,4-difluoro-phenyl)-5-methyl-isoxazole-4-carbonyl]-2-trichloroacetyl-1H-pyrrole (intermediate 19) and cyclopropylmethylamine (commercially available) in 35.8 yield. (m/e): 386.1 (MH+; 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538132B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-fc47efa4ac694ed68921e4ac10709eff |
| Source note | uspto-grants-2009_05 |