HCID 58907415, compound → HCID 23032549, compound

HRID 494432Notes

Reaction equation

HRID 494432 reaction equation
[O:1]=[C:2]([CH3:16])[CH2:3][C:4]1[CH:5]=[C:6](/[CH:10]=[CH:11]/[C:12]([O:14][CH3:15])=[O:13])[CH:7]=[CH:8][CH:9]=1>[Pd].C(O)C>[CH3:15][O:14][C:12](=[O:13])[CH2:11][CH2:10][C:6]1[CH:7]=[CH:8][CH:9]=[C:4]([CH2:3][C:2](=[O:1])[CH3:16])[CH:5]=1

Participants

4

Reactant 1

HCID 58907415HCID 58907415, compound

Product 1

HCID 23032549HCID 23032549, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

A suspension of methyl (2E)-3-[3-(2-oxopropyl)phenyl]acrylate (5.00 g, Preparation 138) and 10% palladium on carbon (500 mg) in ethanol (50 ml) was stirred under an atmosphere of hydrogen (60 psi) at room temperature for 16 hours. The catalyst was filtered off through arbocel and the filtrate concentrated in vacuo to give the title compound as a pale yellow oil which was used without further purification.

Workup

  1. filtrationThe catalyst was filtered off through arbocel
  2. concentrationthe filtrate concentrated in vacuo

Sources & evidence

ORD record
ord-99e7778a94b74c049042f6311b63187b
Source dataset
uspto-grants-2009_05
Patent number
US07538141B2

Reaction notes

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