反应详情

温度

-78 °C

9-Acetyl-carbazole (41.85 g, 0.2 mol) was dissolved in 1 L methylene chloride and 28.5 mL acetylchloride (0.4 mol) and 120 g aluminum chloride (0.9 mol) were added and the solution refluxed for 1.5 h. The solution was cooled to −78° C. and 6N HCl was added slowly while stirring and allowed to warm to room temperature. Methylene chloride was added to dissolve the precipitate and the solution was extracted, and the organics dried over Na2SO4, decolorized with charcoal, filtered and concentrated. Recrystallization from benzene/hexane gave 27.9 g 2,9-diacetylcarbazole.

1. temperaturethe solution refluxed for 1.5 h
2. temperatureto warm to room temperature
3. dissolutionto dissolve the precipitate
4. extractionthe solution was extracted
5. dry with materialthe organics dried over Na2SO4
6. filtrationfiltered
7. concentrationconcentrated
8. customRecrystallization from benzene/hexane