Sodium Hydroxide → HCID 44456288, compound

Participants

Reaction Conditions

Reaction Steps

A suspension of the product of Example 41I (0.968 g) in water (5 mL) and treated with 0.997N sodium hydroxide solution (1.78 mL, 1.77 mmol) and stirred at 25° C. for 1 hour. The solution was lyophilized to give the title compound (0.602 g, 60%). 1H NMR (300 MHz, DMSO-d6): δ ppm 0.75 (m, 6H) 1.10 (m, 1H) 1.38 (m, 7H) 1.75 (m, 1H) 2.22 (m, 1H) 2.95 (m, 3H) 7.31 (m, 3H) 7.45 (m, 3H) 8.05 (m, 1H) 9.87 (m, 1H) 15.55 (m, 1H). MS (ESI−) m/z 542 (M−H)−.

Provenance & Evidence