HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Methylpiperidine → 4-(4-{2-[2-(2-Methyl-1-piperidinyl)ethyl]-1-benzofuran-5-yl}benzoyl)morpholine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Methylpiperidine | HCID 7974 | — |
| Reactant | 2-{5-[4-(4-Morpholinylcarbonyl)phenyl]-1-benzofuran-2-yl}ethyl methanesulfonate | HCID 22274531 | — |
| Product | 4-(4-{2-[2-(2-Methyl-1-piperidinyl)ethyl]-1-benzofuran-5-yl}benzoyl)morpholine | HCID 11743550 | — |
Reaction Steps
The product from Example 23D and 2-methyl-piperidine were processed as described in Example 1D to provide the titled compound. 1H NMR (300 MHz, CD3OD) δ 7.82 (m, 1H), 7.74 (d, J=8.1, 2H), 7.56 (m, 2H), 7.52 (d, J=8.1 Hz, 2H), 6.80 (s, 1H), 3.4-3.78 (m, 15H), 1.6-2.1 (m, 6H), 1.46 (d, J=6.3 Hz, 3H); MS (DCI) m/z 433 (M+H)+;
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538138B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-891b225fb56e4a4d930c8ce174477910 |
| Source note | uspto-grants-2009_05 |