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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 494890Generated: October 30, 2026

2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate → 4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile

https://huagongshe.com/reaction/494890

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl MethanesulfonateHCID 11393678—
Reactant(S)-2-methylpyrrolidine hydrobromideHCID 20779371—
Product4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrileHCID 11255988—

Reaction Steps

(2S)-2-Methylpyrrolidine hydrobromide and the product from Example 1C can be processed as described in Example 1D to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07538138B2
Source datasetuspto-grants-2009_05
ORD IDord-dd485778fd2548bbbbec8eb6807602e6
Source noteuspto-grants-2009_05