HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate → 4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-[5-(4-cyanophenyl)-1-benzofuran-2-yl]ethyl Methanesulfonate | HCID 11393678 | — |
| Reactant | (S)-2-methylpyrrolidine hydrobromide | HCID 20779371 | — |
| Product | 4-(2-{2-[(2S)-2-methylpyrrolidinyl]ethyl}-1-benzofuran-5-yl)benzonitrile | HCID 11255988 | — |
Reaction Steps
(2S)-2-Methylpyrrolidine hydrobromide and the product from Example 1C can be processed as described in Example 1D to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538138B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-dd485778fd2548bbbbec8eb6807602e6 |
| Source note | uspto-grants-2009_05 |