反应详情

温度

90 °C

24 ml of ethanol-water (5:1) was added to 1.00 g of 3-methoxy-6-nitro-4-(2-propenyl)benzylalcohol, 1.00 g of iron, and 2.00 g of ammonium chloride. The reaction solution was stirred at 90° C. for 1 hour. Thereafter, the reaction solution was cooled to a room temperature, and insoluble matters were then removed by filtration. The filtrate was concentrated under a reduced pressure. The residue was diluted with ethyl acetate and then washed with water and a saturated sodium chloride aqueous solution. The organic layer was dried over magnesium sulfate and then concentrated under a reduced pressure, so as to obtain 793 mg of the subject compound.

1. temperatureThereafter, the reaction solution was cooled to a room temperature
2. custominsoluble matters were then removed by filtration
3. concentrationThe filtrate was concentrated under a reduced pressure
4. additionThe residue was diluted with ethyl acetate
5. washwashed with water
6. dry with materialThe organic layer was dried over magnesium sulfate
7. concentrationconcentrated under a reduced pressure