HRID494954

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID10583440

未命名化合物

PRODUCTS

生成物

结构：CNC(=O)c1ccc2ccn(C3CCN(CCc4cc5c(cc4OC)CCN(C)C5=O)CC3)c2c1

HCID57682923

未命名化合物

PROCEDURE

实验过程

The subject compound was synthesized from 6-hydroxy-2-methyl-3,4-dihydro-2H-isoquinolin-1-one (CAS#: 308110-07-8) according to the methods described in Example 22, (1), (2) and (3), and Example 23, (5).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-5e81da7b9daf493aa78098a88cfbf53a
来源数据集: uspto-grants-2009_05
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07538123B2
来源说明: uspto-grants-2009_05

反应 SMILES

OC1C=C2C(=CC=1)[C:8](=[O:12])[N:7]([CH3:13])[CH2:6]C2.COC1C(CCN2CCC(N3C4C(=CC=C(C(N)=O)C=4)C=C3)CC2)=C2C(C(=O)C(C)(C)CO2)=CC=1.C(C1C(OC)=CC2COC(=O)NC=2C=1)C=C.[CH3:65][O:66][C:67]1[C:78]([CH2:79][CH2:80][N:81]2[CH2:86][CH2:85][CH:84]([N:87]3[C:95]4[C:90](=[CH:91][CH:92]=[C:93]([C:96]([NH:98][CH3:99])=[O:97])[CH:94]=4)[CH:89]=[CH:88]3)[CH2:83][CH2:82]2)=[CH:77][C:70]2N(C)C(=O)O[CH2:74][C:69]=2[CH:68]=1>>[CH3:65][O:66][C:67]1[CH:68]=[C:69]2[C:70](=[CH:77][C:78]=1[CH2:79][CH2:80][N:81]1[CH2:86][CH2:85][CH:84]([N:87]3[C:95]4[C:90](=[CH:91][CH:92]=[C:93]([C:96]([NH:98][CH3:99])=[O:97])[CH:94]=4)[CH:89]=[CH:88]3)[CH2:83][CH2:82]1)[C:8](=[O:12])[N:7]([CH3:13])[CH2:6][CH2:74]2