HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → Ethyl (4-iodophenyl)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Sulfuric Acid | HCID 1118 | — |
| Reactant | 4-Iodophenylacetic acid | HCID 137214 | — |
| Product | Ethyl (4-iodophenyl)acetate | HCID 14974990 | 90% |
Reaction Steps
4-Iodophenylacetic acid (3 g), ethanol (20 mL) and conc. H2SO4 (5 mL) were refluxed overnight. Ca. 15 mL ethanol was then evaporated, the residue was extracted with dichloromethane (3×100 mL), the combined organic extracts were washed with sat. aq. NaHCO3, dried over Na2SO4 and evaporated in vacuo to afford 2.97 g (90%) of 121JP58 as a yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07538222B2 |
| Source dataset | uspto-grants-2009_05 |
| ORD ID | ord-cb397d3af94241c2a8071375f0fb4a7e |
| Source note | uspto-grants-2009_05 |