Hydrochloric Acid → HCID 23147049, compound

Participants

Reaction Conditions

Reaction Steps

In the same manner as in the step 2 in Example 25, 4-bromo-1,5-bis(methoxymethoxy)-3-(3-methoxypropyl)-2-phenylbenzene (37.2 mg, 0.0875 mmol) was dissolved in ethanol (4 mL), and concentrated hydrochloric acid (0.1 mL) was added thereto and stirred at 60° C. for 1.1 hours. The reaction liquid was concentrated under reduced pressure, and the resulting residue was purified through partitioning thin-layer chromatography (chloroform/methanol=20/1) to obtain Compound 97 (28.7 mg, 97%).

Provenance & Evidence