2-Bromoethanol → 3-(2-hydroxyethyl)-1,2,3-benzotriazin-4(3H)-one

HRID 495360Notes

Reaction equation

HRID 495360 reaction equation
[N:1]1[C:6]2[CH:7]=[CH:8][CH:9]=[CH:10][C:5]=2[C:4](=[O:11])[NH:3][N:2]=1.Br[CH2:13][CH2:14][OH:15]>>[OH:15][CH2:14][CH2:13][N:3]1[C:4](=[O:11])[C:5]2[CH:10]=[CH:9][CH:8]=[CH:7][C:6]=2[N:1]=[N:2]1

Participants

3

Reactant 2

HCID 108982-BromoethanolHCID 1354087931,2,3-Benzotriazin-4(1H)-one

Product 1

HCID 37800283-(2-hydroxyethyl)-1,2,3-benzotriazin-4(3H)-one

Procedure

3-(2-hydroxyethyl)-1,2,3-benzotriazin-4(3H)one was prepared according to the general procedure outlined in example 1, step 1. Starting from 1,2,3-benzotriazin-4(3H)one (1.5 g, 10 mmol) and 2-bromoethanol (1.68 mL, 20 mmol), 1.20 g (63%); off white solid; m.p. 114° C., MS: 191.9 (M+H)+

Sources & evidence

ORD record
ord-d872d702d7564b169487415709b13bba
Source dataset
uspto-grants-2005_09
Patent number
US06939870B2

Reaction notes

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