HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-(N,N-bis(2-chloroethyl)amino)-1,4-benzodioxane → 6-[4(4-(5-Ethoxycarbonylbenzimidazol-1-yl)butyl)piperazino]-1,4-benzodioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-(N,N-bis(2-chloroethyl)amino)-1,4-benzodioxane | HCID 19797313 | — |
| Reactant | 1-(4-Aminobutyl)-5-ethoxycarbonylbenzimidazole | HCID 19797335 | — |
| Product | 6-[4(4-(5-Ethoxycarbonylbenzimidazol-1-yl)butyl)piperazino]-1,4-benzodioxane | HCID 19797322 | — |
Reaction Steps
Analogously to Example 3, reaction of 1-(4-aminobutyl)-5-ethoxycarbonylbenzimidazole with 6-(N,N-bis(2-chloroethyl)amino)-1,4-benzodioxane ("B") gives 6-[4(4-(5-ethoxycarbonylbenzimidazol-1-yl)butyl)piperazino]-1,4-benzodioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05242925 |
| Source dataset | uspto-grants-1993_09 |
| ORD ID | ord-776d210858d547fca9d654d698089e84 |
| Source note | uspto-grants-1993_09 |