Hydrochloric Acid → Carbamic acid, (2,4-dichlorophenyl)-, ethyl ester

HRID 495647Notes

Reaction equation

HRID 495647 reaction equation
[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH2:4].Cl[C:11]([O:13][CH2:14][CH3:15])=[O:12].Cl>N1C=CC=CC=1>[Cl:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH:4][C:11](=[O:12])[O:13][CH2:14][CH3:15]

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 10928Ethyl chloroformateHCID 111232,4-Dichloroaniline

Product 1

HCID 80626Carbamic acid, (2,4-dichlorophenyl)-, ethyl esterYield 99%

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2,4-Dichloroaniline (2.380 g) was dissolved in pyridine (20 ml), and to the solution was added dropwise ethyl chloroformate (1.685 ml) under ice-cooling. After the mixture was stirred for 2 hours, 1N hydrochloric acid was added. The precipitated crystals were filtered, washed with water and then dried to give the title compound (3.4055 g, 99%).

Workup

  1. temperaturecooling
  2. filtrationThe precipitated crystals were filtered
  3. washwashed with water
  4. customdried

Sources & evidence

ORD record
ord-deb66250e43e4b57b04736706f0d7ea1
Source dataset
uspto-grants-2005_09
Patent number
US06939887B2

Reaction notes

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