Hydrochloric Acid → HCID 131725119, compound

Participants

Reaction Steps

To a stirred solution of 71 mg of N-(cyclopropylmethyl)-N′-[4-[2-[[(2R)-2-hydroxy-2-(3-pyridinyl)ethyl]amino]-2-methylpropyl]phenyl]-sulfamide (2B) in MeOH (1.5 mL) was added 4 N hydrochloric acid in p-dioxane (0.42 mL). After 10 minutes, the reaction solution was concentrated in vacuo to afford 75 mg of the title compound (2C) as a white solid; ms (Cl) m/z=419.4 (M+1). 1H NMR (CDCl3) was consistent with compound (2C).

Provenance & Evidence