HCID 22461733, compound → HCID 21339496, compound

HRID 495962Notes

Reaction equation

HRID 495962 reaction equation
[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:5]=1[O:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[N+:19]([O-])=O>CO.[Pd].C(O)C>[CH3:1][O:2][C:3](=[O:22])[C:4]1[CH:9]=[CH:8][C:7]([O:10][CH3:11])=[CH:6][C:5]=1[O:12][C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][C:14]=1[NH2:19]

Participants

5

Reactant 1

HCID 22461733HCID 22461733, compound

Product 1

HCID 21339496HCID 21339496, compound

Reagents, catalysts & solvents 3

HCID 23938PalladiumCatalystHCID 702EthanolSolventHCID 887MethanolSolvent

Procedure

A solution of 1-1 (7.360 g, 21.87 mmol) in methanol (200 mL) was added to a suspension of 10% palladium on carbon in ethanol (100 mL). The mixture was stirred under hydrogen gas pressure at room temperature for 3 hours. The reaction mixture was filtered through celite and the filtrate evaporated in vacuo to afford the title compound 1-2 as an oil.

Workup

  1. filtrationThe reaction mixture was filtered through celite
  2. customthe filtrate evaporated in vacuo

Sources & evidence

ORD record
ord-e3e816261f3b459bbe1edda35f7319ac
Source dataset
uspto-grants-2005_09
Patent number
US06943156B2

Reaction notes

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