反应详情

To a solution of 5 mL (37.5 mmole) 1-tetralone in 25 mL ethanol was added 2.7 mL (40 mmole) of 50% hydroxylamine in water. The reaction mixture was heated under reflux for 2 hrs, then stirred at room temperature for 16 hrs. The solution was concentrated under reduced pressure. The residue was recrystallized from toluene/hexane to give 1-tetralone oxime (3,4-dihydro-2H-naphthalen-1-one oxime), 3.86 g, m.p. 101-102°.

1. temperatureThe reaction mixture was heated
2. temperatureunder reflux for 2 hrs
3. concentrationThe solution was concentrated under reduced pressure
4. customThe residue was recrystallized from toluene/hexane