Benzaldehyde → 2-phenyl-2,3-dihydroquinazolin-4(1h)-one

HRID 496092Notes

Reaction equation

[C:1]([NH2:10])(=[O:9])[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[NH2:4].[CH:11](=O)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1>>[C:12]1([CH:11]2[NH:10][C:1](=[O:9])[C:2]3[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=3)[NH:4]2)[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1

Participants

Reactant 2

HCID 240Benzaldehyde

HCID 6942Anthranilamide

Product 1

HCID 2708002-phenyl-2,3-dihydroquinazolin-4(1h)-one

Procedure

Anthranilamide was transformed by Method G (using benzaldehyde). M.p. 221-222° C.

Sources & evidence

ORD record: ord-9652c532a39f43a5b35166af29329513
Source dataset: uspto-grants-2005_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06943159B1

Reaction notes

Loading…