Piperidine → HCID 17793541, compound

HRID 496373Notes

Reaction equation

[CH3:1][O:2][C:3]1[C:4](=[O:23])[C:5]([CH3:22])=[C:6]([CH2:12][C:13]2[CH:14]=[C:15](C=C[CH:21]=2)[C:16](O)=O)[C:7](=[O:11])[C:8]=1[O:9][CH3:10].[NH:24]1CCCCC1>>[CH3:1][O:2][C:3]1[C:4](=[O:23])[C:5]([CH3:22])=[C:6]([CH2:12][CH:13]2[CH2:14][CH2:15][CH2:16][NH:24][CH2:21]2)[C:7](=[O:11])[C:8]=1[O:9][CH3:10]

Participants

Reactant 2

HCID 8082Piperidine

HCID 9796974HCID 9796974, compound

Product 1

HCID 17793541HCID 17793541, compoundYield 37%

Procedure

3-(5,6-dimethoxy-3-methyl-1,4-benzoquinon-2-ylmethyl)benzoic acid (85 mg, 0.27 mmol) obtained in Example 41 and piperidine (0.036 ml, 0.41 mmol) were used, and a method similar to that described in Example 42 was employed to obtain the title compound (40 mg, 0.10 mmol, yield 37%).

Sources & evidence

ORD record: ord-10f1d039bde146218220228b06af4fe5
Source dataset: uspto-grants-2005_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06943196B1

Reaction notes

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