反应详情

According to step (a) in the method of example 19a, 5-Chloromethyl-6-hydroxy-3,4-dihydro-2H-naphthalen-1-one (0.211 g, 1.0 mmol) was combined with triethylamine (0.167 ml, 1.2 mmol) in pentan-3-ol (3 ml, Aldrich Chemical) to produce 248 mg of desired product as an orange-red oil. Low resolution mass spectrum (APCI) m/z 263 [M+H]+.