HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylimidazole → 1-methyl-3-[1-(4-nitrophenyl)pyrrolidin-3-yl]-3H-imidazol-1-ium methanesulphonate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylimidazole | HCID 1390 | — |
| Reactant | 1-(4-Nitrophenyl)pyrrolid-3-yl methanesulphonate | HCID 12067814 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 1-methyl-3-[1-(4-nitrophenyl)pyrrolidin-3-yl]-3H-imidazol-1-ium methanesulphonate | HCID 12067815 | 81.4% |
Reaction Steps
23 g (0.08 mol) of 1-(4-nitrophenyl)pyrrolidin-3-yl methanesulphonate (2) was heated for 8 hours at 85° C. in 150 g of 1-methylimidazole (1.82 mol). This solution was stirred in 2 l of ethyl acetate to the point of crystallization. After filtration and drying, 24 g of yellow powder (3) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06946005B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-34012a2670c845dba9780f432371aa79 |
| Source note | uspto-grants-2005_09 |