Diethyl Oxalate → Ethyl oxo-quinolin-5-ylacetate

HRID 496600Notes

Reaction equation

Br[C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2.[C:12](OCC)(=[O:18])[C:13]([O:15][CH2:16][CH3:17])=[O:14]>>[O:18]=[C:12]([C:2]1[CH:11]=[CH:10][CH:9]=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[N:7]2)[C:13]([O:15][CH2:16][CH3:17])=[O:14]

Participants

Reactant 2

HCID 7268Diethyl Oxalate

HCID 8173215-Bromoquinoline

Product 1

HCID 57455371Ethyl oxo-quinolin-5-ylacetate

Procedure

Prepared from 5-bromoquinoline and diethyl oxalate using Method KE-A.

Sources & evidence

ORD record: ord-bc508435c43243ea949c9da2d5304be8
Source dataset: uspto-grants-2005_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06946467B2

Reaction notes

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