Hydrochloric Acid → 3-Bromo-2-methyl-6-methylsulfonylbenzaldehyde

HRID 49678Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 49678
[Br:1][C:2]1[C:3]([CH3:15])=[C:4]([C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:9][CH:10]=1)[CH:5]=NO.Cl.C=[O:18].O>O1CCCC1>[Br:1][C:2]1[C:3]([CH3:15])=[C:4]([C:8]([S:11]([CH3:14])(=[O:13])=[O:12])=[CH:9][CH:10]=1)[CH:5]=[O:18]

Komponenten

6

Edukt 4

HCID 313Hydrochloric AcidHCID 712Formaldehyde2×HCID 962WaterHCID 734619443-Bromo-2-methyl-6-methylsulfonylbenzaldoxime

Produkt 1

HCID 187572773-Bromo-2-methyl-6-methylsulfonylbenzaldehyde

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

7.1 g of 3-bromo-2-methyl-6-methylsulfonylbenzaldoxime (23 mmol) are stirred in a mixture of 17 g of 5% strength hydrochloric acid, 2 g of a 37% strength solution of formaldehyde, 15 ml of water and 30 ml of tetrahydrofuran at 65° C. for 32 hours. During this time, a further 3.5 g of a 37% strength solution of formaldehyde are added in portions of 0.5 g. The mixture is subsequently cooled to room temperature, and the product is filtered off with suction.

Aufarbeitung

  1. filtrationthe product is filtered off with suction

Quellen und Nachweise

ORD-Eintrag
ord-4f8a9d97544f446aac3fa9484e3f63b0
Quelldatensatz
uspto-grants-2004_03
Patentnummer
US06706886B2

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