HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylacetic Acid → HCID 69735012, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylacetic Acid | HCID 999 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Methylmorpholine | HCID 7972 | — |
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | 1,3-Propanediamine, N'-(ethylcarbonimidoyl)-N,N-dimethyl-, monohydrochloride | HCID 2723939 | — |
| Reactant | 4-(2-Methylsulfonylphenyl)aniline | HCID 10800516 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69735012 | HCID 69735012 | — |
Reaction Steps
A solution of 102 mg (0.330 mmol) of [3-(5-methyl[1,2,4)]oxadiazol-3-yl)phenoxy]-2-phenylacetic acid, 81.6 mg (0.330 mmol) of 2′-methanesulfonylbiphenyl-4-ylamine, 63.3 mg (0.330 mol) of N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (DAPECI) and 44.6 mg (0.330 mmol) of 1-hydroxybenzotriazole (HOBt) in 5 ml of DMF is treated with 0.036 ml (0.33 mmol) of 4-methylmorpholine and stirred at room temperature for 18 hours. The reaction mixture is added to water and the precipitate is filtered off. A colourless solid is obtained; FAB 540
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06946489B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-b7a4450eb6c14346967b8bcd53fbee3b |
| Source note | uspto-grants-2005_09 |