Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl [[(methoxycarbonyl)amino](methylthio)methylene]carbamate | HCID 98708 | — |
| Reactant | HCID 10263505 | HCID 10263505 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 140382079 | HCID 140382079 | — |
Reaction Steps
Methyl 3-amino-4-(3-thienylmethyl)-1H-pyrrole-2-carboxylate, obtained from Example 14 (11.8 g, 0.05 mol), N,N′-bis-carbomethoxy-S-methylisothiourea (11.3 g, 0.055 mol) and triethylamine were stirred together in dimethyl formamide (100 mL) and cooled to 5° C. Mercuric chloride (14.9 g, 0.055 mol) was added and an immediate precipitate was observed. The mixture was stirred at room temperature overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06946554B2 |
|---|
| Source dataset | uspto-grants-2005_09 |
|---|
| ORD ID | ord-1c97259a2d464ec4acd8dda035eaa939 |
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| Source note | uspto-grants-2005_09 |
|---|
