Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Methyl [[(methoxycarbonyl)amino](methylthio)methylene]carbamate | HCID 98708 | — |
| Reactant | HCID 10036874 | HCID 10036874 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 140382078 | HCID 140382078 | — |
Reaction Steps
Methyl 3-amino-4-(3-pyridylmethyl)-1H-pyrrole-2-carboxylate, obtained from Example 16 (2.31 g, 0.01 mol), N,N′-bis-carbomethoxy-S-methylisothiourea (2.27 g, 0.011 mol) and triethylamine (3.6 g, 0.35 mol) were stirred together in acetonitrile (50 mL) and cooled to 5° C. Mercuric chloride (2.98 g, 0.011 mol) was added and an immediate precipitate was observed. The mixture was stirred at room temperature overnight.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06946554B2 |
|---|
| Source dataset | uspto-grants-2005_09 |
|---|
| ORD ID | ord-439d56c742f2488383d55456a7e87fb5 |
|---|
| Source note | uspto-grants-2005_09 |
|---|
