HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1-Methyl-1H-1,2,4-triazol-3-yl)methanol → 6-(2-Methyl-1,2,4-triazol-5-yl)methyloxy-3-(isoxazol-3-yl)imidazo[5,1-a]phthalazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1-Methyl-1H-1,2,4-triazol-3-yl)methanol | HCID 10351670 | — |
| Reactant | 6-Chloro-3-(isoxazol-3-yl)-imidazo[5,1-a]phthalazine | HCID 22318516 | — |
| Product | 6-(2-Methyl-1,2,4-triazol-5-yl)methyloxy-3-(isoxazol-3-yl)imidazo[5,1-a]phthalazine | HCID 22318519 | — |
Reaction Steps
The title compound was prepared from 6-chloro-3-(isoxazol-3-yl)-imidazo[5,1-a]phthalazine (Part b) and (2-methyl-1,2,4-triazol-5-yl)methanol as described in Example 1, Part c. 1H NMR (360 MHz, CDCl3) δ 3.96 (s, 3H), 5.7 (s, 2H), 7.40 (s, 1H), 7.52 (t, J=8 Hz, 1H), 7.76 (t, J=8 Hz, 1H), 7.89 (s, 1H), 8.0 (d, J=8 Hz, 1H), 8.17 (d, J=8 Hz, 1H), 8.56 (s, 1H). MS (ES+) m/e 348 [MH]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06949549B2 |
| Source dataset | uspto-grants-2005_09 |
| ORD ID | ord-8c9dac29bed34dd1b24e187b7f8178b9 |
| Source note | uspto-grants-2005_09 |