反应详情

温度

40 °C

0.05 g of methyl 3-chloro-5-(3,3-dichloroprop-2-enyloxy)-2-[3-(5-trifluoromethylpyrid-2-yloxy)propyloxy]benzoate and 0.028 g of propionamidoxime were dissolved in 1 ml of anhydrous ethanol. A solution of 0.008 g of sodium in 0.5 ml of ethanol was added to this solution. The mixture was stirred at 40° C. for 2 hours and at room temperature for 20 hours. The mixture was then concentrated, and diethyl ether and water were added. After shaking, the ether phase was isolated, dried and concentrated under reduced pressure, and the crude product was purified chromatographically. Yield: 0.017 g (32%)

1. concentrationThe mixture was then concentrated
2. additiondiethyl ether and water were added
3. stirringAfter shaking
4. customthe ether phase was isolated
5. customdried
6. concentrationconcentrated under reduced pressure
7. customthe crude product was purified chromatographically