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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 497241Generated: October 31, 2026

3-Fluoro-4-sulfamoylphenylhydrazine hydrochloride → 4-[5-[3-Chloro-4-(2-furyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-fluorobenzenesulfonamide

https://huagongshe.com/reaction/497241

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluoro-4-sulfamoylphenylhydrazine hydrochlorideHCID 22316669—
Reactant1-[3-Chloro-4-(2-furyl)phenyl]-4,4,4-trifluoro-1,3-butanedioneHCID 22316700—
Product4-[5-[3-Chloro-4-(2-furyl)phenyl]-3-(trifluoromethyl)-1H-pyrazol-1-yl]-2-fluorobenzenesulfonamideHCID 22316710—

Reaction Steps

The title compound was prepared according to the procedure of Example 60 using 3-fluoro-4-sulfamoylphenylhydrazine hydrochloride instead of 3-fluoro-4-(methylsulfonyl)phenylhydrazine hydrochloride and 4,4,4-trifluoro-1-[3-chloro-4-(2-furyl)phenyl]butane-1,3-dione instead of 4,4,4-trifluoro-1-[4-(2-furyl)phenyl]butane-1,3-dione in step 2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949536B2
Source datasetuspto-grants-2005_09
ORD IDord-b01d2354227d481c84abc108ad8674c6
Source noteuspto-grants-2005_09