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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 497292Generated: October 27, 2026

3-Fluorobenzyl bromide → 1-(4-Bromo-3-methylphenyl)-2-(3-fluorophenyl)ethanone

https://huagongshe.com/reaction/497292

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Fluorobenzyl bromideHCID 68007—
Reactant4-Bromo-3-methylbenzoyl chlorideHCID 7021534—
Product1-(4-Bromo-3-methylphenyl)-2-(3-fluorophenyl)ethanoneHCID 17923417—

Reaction Steps

The title compound was prepared according to the procedure of step 3 in the Example 169 using 3-fluorobenzyl bromide and 4-bromo-3-methylbenzoyl chloride (Cignarella; G.; Curzu, M. M.; Grella, G.; Loriga, M.; Anania, V.; Desole, M. S.; J. Farmaco. Ed. Sci., 1983, 38, 187-198.).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06949536B2
Source datasetuspto-grants-2005_09
ORD IDord-3d9fe5bbbab947a284e575064c4ecd79
Source noteuspto-grants-2005_09